What does KERA stand for?

KERA stands for various terms. Discover the full forms, meanings, and possible interpretations of KERA across different fields and industries.

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Keratitis

Keratitis refers to the inflammation of the cornea, the eye's clear front surface, which can result from infection, injury, or underlying diseases. Symptoms often include pain, redness, blurred vision, and sensitivity to light. Prompt treatment is essential to prevent complications such as corneal scarring or vision loss.

The condition can be classified into infectious and non-infectious types, with bacterial, viral, fungal, and parasitic pathogens being common culprits in the former. Contact lens wearers are at higher risk due to potential microbial contamination. Advances in diagnostic techniques and antimicrobial therapies have improved outcomes for patients suffering from keratitis, making early detection and treatment pivotal.

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Keratocan

Keratocan is a protein that in humans is encoded by the KERA gene. It is a member of the small leucine-rich proteoglycan (SLRP) family and plays a crucial role in the maintenance of corneal transparency. Mutations in the KERA gene have been associated with cornea plana, a condition characterized by a flat cornea leading to hyperopia and other visual impairments.

The protein's structure allows it to interact with collagen fibrils, contributing to the regular spacing and diameter necessary for corneal transparency. Research into Keratocan has provided insights into corneal diseases and potential therapeutic targets. Its expression is predominantly in the cornea, making it a key subject in ophthalmology and genetic studies related to eye disorders.

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How is KERA used?

  • Diagnosing KERA (Keratitis) early is crucial in the Medical field to administer the appropriate treatment and prevent permanent damage to the patient's vision.
  • In the study of corneal diseases, KERA (Keratocan) mutations are often investigated due to their significant impact on corneal structure and transparency, highlighting its importance in the Medical field.

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