SCLER has various meanings in the Physiology category. Discover the full forms, definitions, and usage contexts of SCLER in Physiology.
Scleroderma is a long term autoimmune disease that results in hardening of the skin. In the more severe form, it also affects internal organs. The cause is unknown. The underlying mechanism involves the body's immune system attacking healthy tissues. There is a strong association with certain mutations in HLA genes. Environmental factors have also been implicated.
PhysiologyLocalized hardening of skin. Sclerosis is generally caused by underlying diseases, such as diabetes and scleroderma. Treatment is directed toward the cause.
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