WED Medical Abbreviation

Willis-Ekbom Disease

Willis-Ekbom Disease (WED), commonly referred to as Restless Legs Syndrome (RLS), is a neurological disorder characterized by an irresistible urge to move the legs, often accompanied by uncomfortable sensations. These symptoms typically occur in the evening or night when the individual is at rest, leading to difficulty in falling or staying asleep. The exact cause of WED remains unclear, but it is believed to involve genetic factors and abnormalities in the dopaminergic system. Treatment options include lifestyle changes, iron supplementation, and medications that affect dopamine levels or other neurotransmitters.

Research into Willis-Ekbom Disease has highlighted its significant impact on quality of life, with many patients reporting sleep disturbances, daytime fatigue, and emotional distress. The condition can be primary, with no known underlying cause, or secondary, resulting from conditions such as iron deficiency, pregnancy, or chronic kidney disease. Diagnosis is primarily clinical, based on patient history and symptom description, as there are no specific tests for WED. Awareness and understanding of the disease are crucial for effective management and improving patient outcomes.