What does XLR stand for?

X-Linked Recessive

X-Linked Recessive refers to a mode of genetic inheritance where a mutation on the X chromosome leads to a disorder that is more commonly observed in males, due to their single X chromosome. Females, with two X chromosomes, are typically carriers unless both copies are affected. This pattern of inheritance is responsible for a variety of genetic conditions, including hemophilia and Duchenne muscular dystrophy, highlighting the importance of genetic counseling in families with a history of such disorders.

Understanding X-Linked Recessive inheritance is crucial for medical professionals when diagnosing and managing genetic diseases. It allows for accurate risk assessment and informed decision-making regarding family planning and preventive measures. The study of these genetic patterns also contributes to advancements in gene therapy and targeted treatments, offering hope for conditions that were once considered untreatable.