ZES Medical Abbreviation

ZES has various meanings in the Medical category. Discover the full forms, definitions, and usage contexts of ZES in Medical.

Zollinger-Ellison Syndrome

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Zollinger-Ellison syndrome is a rare condition in which one or more tumors form in your pancreas or the upper part of your small intestine. These tumors, called gastrinomas, secrete large amounts of the hormone gastrin, which causes your stomach to produce too much acid.

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Zollinger Ellison Syndrome
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Zutphen Elderly Study
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Zollinger–Ellison syndrome

Zollinger–Ellison syndrome (ZES) is a Gastrinoma which is a neuroendocrine tumor that secretes Gastrin; resultant hypergastrinemia causes gastric acid hypersecretion. This leads to growth of gastric mucosa, increase in number of Parietal cells and proliferation of gastric ECL cells. Most Gastrinomas are present in duodenum (50-70%), pancreas ( 20-40%) and other intraabdominal site.

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